Updated 4:25 p.m.

A Colfax woman was one of two people injured in a three-vehicle crash near Julian in Guilford County early Wednesday that killed three people.

Marie Michalicova Beazlie, 39, of Colfax was seriously injured and was taken to Wake Forest Baptist Medical Center in Winston-Salem, the Highway Patrol said in a news release.

Courtney Nicole Chrisco, 22, of Olivia was taken to Moses Cone Hospital for injuries not considered life-threatening, the patrol said.

Troopers responded about 7:50 a.m. Wednesday to a wreck on U.S. 421 North near the N.C. 62 exit.

Chrisco's 2013 Toyota passenger car struck the rear of a 1992 Jeep that was moving slowly due to mechanical issues, the patrol said. The two vehicles both caught fire after the crash, with the Jeep ending in the median and Chrisco's car stopped in the road. 

Beazlie, trying to avoid the crash, ran off the road and her 2005 Honda SUV collided with the Jeep. Her vehicle also caught on fire, the patrol said.

The driver and two passengers in the Jeep died at the scene, the patrol said. Their names have not been released pending positive identification, troopers said. 

The patrol is asking that anyone who saw what happened to contact them at 336-256-2058.

Updated at 2:45 p.m.

Three people were killed and two others were sent to area hospitals after a collision involving three vehicles on U.S. 421 on Wednesday morning.

State troopers responded to the wreck at 7:48 a.m., said Highway Patrol spokesman Brandon Baker.

A preliminary report showed that an SUV was stopped in the northbound lane north of the N.C. 62 exit, Baker said. Two other vehicles, another SUV and a car, hit the first SUV. One of the SUVs and the car went into the median and caught fire.

Three people in one of the SUVs were killed. The driver of the other SUV was sent to Wake Forest Baptist Medical Center in Winston-Salem. The driver of the car was sent to Moses Cone Hospital in Greensboro.

Baker said it is so far unclear which SUV the fatalities were in as the investigation continues.

Identities of the victims are expected to be released later Wednesday.

Northbound traffic was rerouted onto the N.C. 62 exit. According to the N.C. Department of Transportation website, the northbound lane has reopened.

A deadly vehicle crash on U.S. 421 Wednesday morning closed the northbound lane near N.C. 62.

One person was killed in the fiery crash near milemarker 189 heading north, WGHP-Channel 8 reported.

Northbound traffic was rerouted onto the N.C. 62 exit. The N.C. Department of Transportation estimates the road will reopen at 2 p.m.

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